A novel technology to formulate and bioactivate spider silk protein

By imitation of Nature's high-performance material - the spider silk - we are able to produce a defined protein that self-assembles into a strong, elastic, biocompatible and biodegradable material.
The whole process is performed under benign conditions, using only water-based buffers. By the use of recombinant DNA technology, we are able to incorporate various bioactive molecules, e.g. cell adhesion motifs, growth factors, enzymes, and affinity domains.
The bioactive silk proteins obtained have the unique ability to efficiently assemble into strong and elastic microfibers in 2D and 3D arrangements.

Various applications:

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Cell adhesion motifs

Antimicrobial peptides

Affinity domains

Formulation of Spiber® silk materials

After expression and purification under native conditions, the spider silk proteins can self-assemble into several formats.

Fiber bundles

Fiber bundles support directional cell growth along the fibers.

Film

Films are free-standing, thin, transparent and lightweight materials.

Foam

Foam is a soft, flexible three dimensional scaffold.

Coating

Coatings provide immobilization of functional units onto various base materials.