A novel technology to formulate and bioactivate spider silk
By imitation of Nature's high-performance material - the spider silk - we are able to produce a defined protein that self-assembles into a strong, elastic, biocompatible and biodegradable material.
The whole process is performed under benign conditions, using only water-based buffers. By the use of recombinant DNA technology, we are able to incorporate various bioactive molecules, e.g. cell adhesion motifs, growth factors, enzymes, and affinity domains.
The bioactive silk proteins obtained have the unique ability to efficiently assemble into strong and elastic microfibers in 2D and 3D arrangements.
Cell adhesion motifs
After expression and purification under native conditions, the spider silk proteins can self-assemble into several formats.
Fiber bundles support directional growth along the fibers.
Films are free-standing, thin, transparent and lightweight materials.
Foam is a soft, flexible three dimensional scaffold.
Coatings provide Immobilization of functional units onto various base materials.